Mary G. and Robert G. Lane Early Career Chair Associate Professor of Biomedical Engineering and Cardiovascular Medicine MEMS and nano sensors, reactive nitrogen species (RNS) and reactive oxygen species (ROS), vascular endothelial dynamics, and molecular imaging of atherosclerotic lesions.
Dr. Hsiai received his undergraduate education from Columbia University and his MD from the University of Chicago. He completed his internship, residency and NIH-funded cardiovascular fellowship at UCLA School of Medicine, during which he also obtained a PhD in Biomedical Engineering in 2001. Dr. Hsiai is board certified by the American Board of Internal Medicine and Cardiovascular Disease. He also holds a joint appointment with the Keck School of Medicine at the Division of Cardiovascular Medicine. His research program is funded by the National Institutes of Health and American Heart Association. He is the Chair for the American Physiological Society Joint Meeting with Biomedical Engineering Society,member of THE American Society for Clinical Investigation, a Fellow of American College of Cardiology, and the recipient of an NIH Physician- Scientist Career Development Award and an American Heart Association John J. Simpson Outstanding Research Achievement Award.
Research
The central theme of Dr. Hsiai's research program is primarily on hemodynamics and mechanobiology via the application of engineering principles and techniques, including Bio-MEMS and nanotechnology to study oxidative stress and to link physical and chemical properties with vascular biology. Using a micro-fluidic flow model, Dr. Hsiai's lab is investigating the mechanisms whereby hemodynamics regulates the development of coronary artery disease. His group is linking the effects of real-time shear stress on cardiac cell dynamics using intravascular polymer sensors, molecular biology techniques, and proteomics. Using zebrafish heart model, the group is developing micro-ECG for longitudinal monitoring for cardiac arrhythmia. The current research objective is to study vascular inflammatory responses in the context of electrochemical properties and vascular calcification.
Dr. Hsiai's research interests include:
* MEMS and nano sensors
* Reactive nitrogen species (RNS) and reactive oxygen species (ROS)
* Vascular endothelial dynamics
* Molecular imaging of atherosclerotic lesions
* To view a photo of a Catheter-Based MEMS Sensor, click here.
